Effects of dexmedetomidine on the recovery profiles from general anesthesia in patients undergoing endoscopic sinus surgery

نویسندگان

  • Kai Xu
  • Yunsong Pan
  • Minmin Zhu
چکیده

Objective: The aim of the present study was to evaluate the effects of dexmedetomidine on the recovery profiles from general anesthesia in patients undergoing endoscopic sinus surgery (ESS). Methods: Sixty patients undergoing ESS under general anesthesia were randomly assigned to two groups. The dexmedetomidine group (Group D) received intravenous administration of dexmedetomidine 0.5 μg/kg after endotracheal intubation, while the control group (Group C) received volume-matched normal saline. Heart rate, mean arterial pressure, and recovery profiles were evaluated during emergence. Results: There was no significant difference between the two groups with respect to the demographic data, durations of surgery and anesthesia, time to eye opening, and time to extubation. The heart rate and mean arterial pressure were more stable in Group D compared with Group C during emergence (P < 0.05). The incidence of emergence agitation and postoperative pain scores were significantly lower in Group D than Group C (P < 0.05). Conclusion: Intraoperative infusion of dexmedetomidine may result in a smooth and favorable recovery profile in patients undergoing ESS under general anesthesia.

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تاریخ انتشار 2016